Constantinos Pantos
Dr. C. Pantos received his degree in Medicine and his PhD from Medical School of Athens. He was trained in Clinical and Invasive Cardiology at the University College & Middlesex Hospital, London, UK.
Dr. C. Pantos received his degree in Medicine and his PhD from Medical School of Athens. He was trained in Clinical and Invasive Cardiology at the University College & Middlesex Hospital, London, UK. He is currently Professor and Head of the Department of Pharmacology, Medical School, University of Athens. He is editor of the book entitled “Myocardial ischemia : from mechanisms to therapeutic potentials” by Cokkinos/ Pantos / Heusch / Taegtmeyer (Eds), Springer, 2006. For the last 20 years, his research is focused on the role of thyroid hormone in tissue regeneration (myocardium, neural tissue, pancreas, sepsis) and especially on endogenous mechanisms of repair/regeneration after myocardial injury. This research has resulted in a Phase II clinical trial (Thy-Repair) testing the effects of T3 in patients with acute myocardial infarction. (EudraCT:2016-000631-40). He has significant experience in design of clinical trials and repositioning of old drugs to other indications. He was one of the clinical experts in the EC funded project “Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications” (PONTE).
Dr. Pantos has published more than 120 scientific papers in international, peer-review journals His work has received more than 3800 citations (Google Scholar, h-index 39). He has also served as a guest editor in 4 special issues. He has several research collaborations with the pharmaceutical industry (Gilead, Menarini, Sanofi-Aventis, Servier, Uni-Pharma Laboratories S.A.)
Iordanis Mourouzis
Dr. Mourouzis received his degree in Medicine from University of Athens (2001) and PhD in “Thyroid hormone and cardioprotection” (2006, University of Athens).
Dr. Mourouzis received his degree in Medicine from University of Athens (2001) and PhD in “Thyroid hormone and cardioprotection” (2006, University of Athens). He is a trained cardiologist and is currently Associate Professor in the Department of Pharmacology, Medical School, University of Athens. He is the scientific coordinator of the GNPAC team. He has considerable experience in experimental models of isolated rat hearts, in vivo model of ischemia-reperfusion, echocardiograqphy in mice and rats, biochemical and molecular techniques. His research is focused on the role of thyroid hormone in tissue repair (myocardium, neural tissue, pancreas, sepsis) and especially on endogenous mechanisms of repair/regeneration after myocardial injury. This research has resulted in a Phase II clinical trial (Thy-Repair) testing the effects of T3 in patients with acute myocardial infarction. (EudraCT:2016-000631-40). He is also involved in several experimental investigations about the role of old and new pharmacological interventions in tissue injury and repair (ranolazine, amiodarone, dronedarone, trimetazidine, dobutamine, clenbuterol, phenylephrine, sildenafil, morphine). He is inventor of 1 international and 3 Greek patents for new drugs.
He was one of the clinical experts in the EC funded project “Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications” (PONTE) and has significant experience in translational research and statistics. He is the scientific coordinator for NKUA in the European program “Regenerating the diabetic heart and kidney by using stress-specific thyroid hormone nanocarriers” (EURONANOMED2019-049 / REASON, 2020-2023)
Dr. Mourouzis has published more than 100 scientific papers in international, peer-review journals. His work has received more than 3300 citations according to Google Scholar (h-index 37). He has published 3 chapters in international scientific books. He is one of the two representatives of National and Kapodistrian University of Athens in the HEALTH HUB Council of the CIVIS program, a European Civic University formed by the alliance of nine leading research higher education institutions across Europe.
Athanassios Trikas
Dr. A. Trikas received his degree in Medicine from University of Athens (1984) and PhD in Cardiology (1991, University of Athens). He is trained in Clinical and Invasive Cardiology at Hippokration Hospital, NKUA.
Dr. A. Trikas received his degree in Medicine from University of Athens (1984) and PhD in Cardiology (1991, University of Athens). He is trained in Clinical and Invasive Cardiology at Hippokration Hospital, NKUA. He has received research award for Heart Failure at the Division of Cardiology, Hammersmith Hospital, RPMS, London, U.K. He is currently Head of Cardiology Department, General Hospital “ELPIS” in Athens. He has published 75 papers in international peer-review journals concerning clinical research in Heart Failure, left atrial physiology, cardiomyopathies, and exercise. His work has received more than 2000 citations according to scopus (h-index 20). He is a member of the GNPAC team investigating the potential novel therapeutic applications of triiodothyronine in Cardiovascular Disease. He was the principal investigator for the recruitment and follow-up of patients in the phase IIa Thy-Repair trial designed to test the effects of T3 in patients with acute myocardial infarction (EudraCT:2016-000631-40) which was completed in December 2020. He has participated as principal investigator in more than 20 clinical trials.
Polyxeni Mantzouratou
Polyxeni Mantzouratou graduated from the Medical School of the National and Kapodistrian University of Athens (UOA). She completed her specialist training in the Cardiology Clinic of the Laiko General Hospital of Athens and acquired the Board Certification in Cardiology in 2019.
Polyxeni Mantzouratou graduated from the Medical School of the National and Kapodistrian University of Athens (UOA). She completed her specialist training in the Cardiology Clinic of the Laiko General Hospital of Athens and acquired the Board Certification in Cardiology in 2019. She is an honour Doctoral Degree Graduate of the National and Kapodistrian University of Athens. The subject of her research is «Novel approaches in the pathophysiology of cardiac remodelling after myocardial infarction: experimental study», which was carried out at the Pharmacology Laboratory of the Medical School (2014). She holds a post-graduate title (M.A.) from the Department of Biomathematics, School of Medicine, University of Thessaly on the subject “Research Methodology in Biomedicine, Biostatistics and Clinical Bioinformatics” (2016). From 2019 to 2021 she was a fellowship scholar of the Laboratory of Organ Regeneration, Department of Molecular Medicine Istituto Di Ricerche Farmacologiche Mario Negri (Bergamo, Italy).
Athanasia – Paraskevi Katsaouni
After completing her secondary education, she was admitted to the School of Chemistry of University of Ioannina, where she graduated in 2017 after preparing her dissertation entitled “Synthesis of peptide analogues and investigation of the action to inhibit MRP4 as a new generation of antithrombotic drug”.
She completed postgraduate studies at the School of Chemistry of University of Ioannina in the field of Synthetic Chemistry - Biochemistry, Bioactive compounds and prepared a Master's thesis entitled: “Design, synthesis and investigation of the inhibitory activity, in human platelet aggregation, of analogs of the intracellular domain Walker B of MRP4”. Since 2019 she has joined the GNPAC research team of the Pharmacology Laboratory and is preparing her doctoral dissertation on : “Study of the effects of new thyroid hormone analogs and stress-specific nanocarriers of T3 in cardiac cell lines and myoblasts”. She is trained and has experience in multiple molecular techniques including Elisa, Luminex, in vitro cell cultures (myoblasts, fibroblasts, cell cancer lines), western blot, immunohistochemistry and immunofluorescence. She participates as a researcher in the European Program EURONANOMED2019-049, Acronym: REASON, title: Regenerating the diabetic heart and kidney by using stress-specific thyroid hormone nanocarriers) which aims to develop nanoparticle drug delivery systems that will be able to target and deliver L- triiodothyronine (T3) specifically in stress cells.
Eleftheria Malaxianaki
She was born in Athens in 1988. After graduating in 2006 from the "Leontio Lyceum of Nea Smyrni", she attended the "National and Kapodistrian University of Athens".She received a degree in Medicine with an excellent grade in 2012.
She was born in Athens in 1988. After graduating in 2006 from the "Leontio Lyceum of Nea Smyrni", she attended the "National and Kapodistrian University of Athens".She received a degree in Medicine with an excellent grade in 2012. Shestarted working as an Internal Medicine resident at the Hospital of Piraeus "Metaxa"(2013-2015) and then she specialized in Cardiology at the General Hospital of Athens "Elpis"(2016-2020). Since 2018she has been working on the elaboration of her doctoral dissertation entitled "Study of the results and mechanisms of action of acute administration of triiodothyronine (T3) in an in vivo model of ischemia / reperfusion in rats", in collaboration with the department of Pharmacology of the Medical School of Athens.She has participated in scientific papers that have been presented at important conferences and have been published in international and Greek scientific journals.
Constantinos Grigoriou
He was born in South Carolina, USA in 1987. After completing his high school education from 2nd Lyceum of Argos with excellent grades, he was accepted to Medical School of the National and Kapodistrian University of Athens (2006-2012) and achieved his graduation with degree “ Very Good” (7 ,79/10).
He was born in South Carolina, USA in 1987. After completing his high school education from 2nd Lyceum of Argos with excellent grades, he was accepted to Medical School of the National and Kapodistrian University of Athens (2006-2012) and achieved his graduation with degree “ Very Good” (7 ,79/10). He trained in Internal Medicine at the " General Hospital of Argolida" (2013-2015) and then he specialized in Cardiology at the General Hospital of Athens "Elpis" (2015-2019). After successful examination (12/2019), he received the title of Cardiologist in 02/2020. In 2017 he started his collaboration as a Phd candidate with the Department of Pharmacology of National and Kapodistrian University of Athens with the thesis "The role of triiodothyronine changes for repair of left ventricle dysfunction and remodelling in STEMI patients" under the supervision of Professor I. Mourouzis. Furthermore he participates as a researcher in important studies of the department. In 2018 he received his Msc degree in "Cardiopulmonary Resuscitation" from the Medical School of Athens with honors (9.65 / 10). He has participated in scientific papers that have been published in international and Greek scientific journals. Since 04/2021 he has been working as consultant Cardiologist at the General Hospital of Athens "Elpis".
Dimitrios Giannoulis
He was born in Kalampaka in 1991. After high school completion with excellent grades, he was accepted in Medical School of University of Crete and achieved his graduation with degree ‘Very Good’.
He was born in Kalampaka in 1991. After high school completion with excellent grades, he was accepted in Medical School of University of Crete and achieved his graduation with degree ‘Very Good’. Afterwards he specialized in Anaesthesiology at the University General Hospital ‘Attikon’. During residency he showed special interest in Regional and Cardiac Anesthesia. He contributed in the authorship of many publications and articles in Greek and European congresses. His interest in cardiac physiology fueled the beginning of his collaboration with the Department of Pharmacology of National and Kapodistrian University of Athens under the auspices of Professors C. Pantos and I. Mourouzis. Since 25/11/2019 he is a PhD candidate with the thesis “The effect of new thyroid analogues in ischemia-reperfusion injury of the heart”. Primary object of this doctoral thesis will be studying the effect of these new thyroid analogues in ischemia-reperfusion injury of cardiac muscle and will be conducted in isolated heart model in rats (Langendorff).
Dimitrios Anagnostopoulos
In 2001, Dr Dimitrios Anagnostopoulos was admitted as an undergraduate student to the Department of Electrical & Computer Engineering, University of Patras, and was awarded with his degree in 2008. Following his military conscription, he began medical studies at the department of Medicine, University of Patras in 2009 and was awarded with a Medical Degree in 2015.
In 2001, Dr Dimitrios Anagnostopoulos was admitted as an undergraduate student to the Department of Electrical & Computer Engineering, University of Patras, and was awarded with his degree in 2008. Following his military conscription, he began medical studies at the department of Medicine, University of Patras in 2009 and was awarded with a Medical Degree in 2015. In the same year, he practiced community family medicine at the Health Centre of Pylos and was placed for 6 months in the Anesthesiology Department of the General University Hospital of Patras.
Since 2017, he has been serving as a trainee doctor in Anesthesiology at the 2nd University Department of Anesthesiology, General University Hospital “Attikon”. Furthermore, in 2018 he start working in basic research at the Pharmacology Lab of the Medical School – National and Kapodistrian University of Athens, as part of his doctoral thesis: “Novel methods of protection for long-term extracorporeal preservation of heart transplants – Relation with transplantation” which is conducted in the isolated rat heart model (Langendorff).
Thomais Lamprou
I am a graduate of the Medical School of the National and Kapodistrian University of Athens as well as a holder of a postgraduate degree in the program of "Interventional Cardiology", NKUA.
I am a graduate of the Medical School of the National and Kapodistrian University of Athens as well as a holder of a postgraduate degree in the program of "Interventional Cardiology", NKUA.
I am doing my specialization in Cardiology at the 2nd Cardiology Clinic of the General State Hospital of Nice. From February 2020, I am involved in basic research in the department of Pharmacology of the Medical School where I became a member of the GNPAC team. I am very interested about experimental cardiology and its very important clinical extensions. Subject of my PhD dissertation is "SAFETY AND EFFICIENCY OF TRIODODYTHRONINE NANO CARRIERS SPECIALISTS AFTER EXPERIMENTAL MYOCARDIUM INFRACTION IN HEALTHY BUT ALSO WITH DIABETES RATS". I am trained in handling laboratory rats and performing experimental acute myocardial infarction via ligation of the left coronary artery as well as in rat echocardiography.
Antonia Pantelidaki
She was born in Crete in 1998. She studied at the University of Peloponnese where she received her degree in Nursing with an excellent grade (2020). She holds a master degree from the Department of Medicine of Democritus University of Thrace entitled "Clinical Pharmacology - Therapeutics" (2022).
She was born in Crete in 1998. She studied at the University of Peloponnese where she received her degree in Nursing with an excellent grade (2020). She holds a master degree from the Department of Medicine of Democritus University of Thrace entitled "Clinical Pharmacology - Therapeutics" (2022). During the follow-up of her postgraduate studies she showed a special interest in the field of basic research and in September 2021 joined the GCardPha Research team in order to expand her field of knowledge and to actively participate in research. Antonia is a contributor in research projects and participates in scientific conferences. From 2022 is a PhD candidate with a doctoral thesis entitled "Dose-dependent study of effectiveness/safety evaluation after triiodothyronine administration in an experimental mouse model of sepsis.".
